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Noting the “no or very limited treatment options” for congenital hyperinsulinism, Zealand Chief Medical Officer David Kendall said the company is “committed to working with the FDA and our third-party manufacturing partner to bring dasiglucagon to patients living with this devastating disease in the months ahead.” September 30 Product: Fresenius Kabi and Formycon’s Otulfi Indication : Crohn’s disease, ulcerative colitis, plaque psoriasis and active psoriatic arthritis There’s a new Stelara biosimilar on the block after the FDA greenlit Otulfi, from partners Fresenius Kabi and Formycon, for the treatment of Crohn’s disease, ulcerative colitis, moderate to severe plaque psoriasis and active psoriatic arthritis—all conditions for which the reference product is also approved
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Studies examining receptor binding have shown that GLP-RT demonstrates strong activity at the human GIP receptor while maintaining measurable activity at both GLP-1 and glucagon receptors, creating a balanced activation profile that allows researchers to explore receptor crosstalk and multi-pathway metabolic signaling [2]
